Mecobalamin injections 500 mcg (vitamin B12)

General information on Japanese Mecobalamin injections 500 mcg

Package details: 50 ampules, 50 mcg (0.5 mg) of active ingredient in each ampoule

Manufacturer: Towa Pharmaceutical, Japan. Established in Osaka in 1951.

Active component: Methylcobalamin (Vitamin B12, 500 mcg in 1 ampoule)

Medical effects: Mecobalamin, one of the coenzyme forms of vitamin B12, has following effects on human body.

• it promotes nucleic acid synthesis in nerves,
• improves protein synthesis in nerves,
• promotes axon regeneration and myelination,
• repaires the injured peripheral nerve to improve numbness and pain.

Therefore, it’s used to treat Vitamin B12 insufficiency and peripheral neuropathy.

Contraindications and precautions: do not use in children, pregnant women and breastfeeding mothers. If an allergic reaction occurs, discontinue use. When used with other drugs, be sure to consult with your doctor. Store away from direct sunlight, heat and moisture. Vitamin B12 is easily damage by the sunlight, so be sure it’s stored in dark place. If the ampoules’ bright pink color started fading, discard them.

Mecobalamin injections 500 mcg from Japan: Dosage and administration 

For adults intramuscular or intravenous injection 1 time a day 3 times a week.

Is Japanese Mecobalamin injection effective?

Mecobalamin 500 mcg injections from Japan are used, primarily, in patients with vitamin B12 deficiency. But the ability to repair peripheral nerves’ axons also makes methylcobalamin effective for treating pain and peripheral neuropathy (Ming Zhang, Wenjuan Han et al. “Methylcobalamin: A Potential Vitamin of Pain Killer”. Neural Plasticity. Volume 2013. http://dx.doi.org/10.1155/2013/424651). Furthermore, clinical studies show that mecobalamin helps to treat neuropathies caused by diabetes (Sunil T.Pai MD. “Peripheral Neuropathy”. Integrative Medicine (Fourth Edition). 2018, Pages 120-132). Moreover, methylcobalamin is prescribed by specialists for treating dementia and improving semen quality, including increased sperm count, enhanced sperm motility and reduced sperm DNA damage (Steven F Werder. “Cobalamin deficiency, hyperhomocysteinemia, and dementia”. Neuropsychiatric Disease and Treatment. 2010; 6: 159–195; Saleem Ali Banihani. “Vitamin B12 and Semen Quality”. Biomolecules. 2017 Jun; 7(2): 42).