Symmetrel (Amantadine) 50 mg from Japan (Parkinson, respiratory tract)

General information about Japanese Symmetrel (Amantadine) 50 mg

Package details: 100 tablets (50 mg in 1 tablet)

Manufacturer: Sun Pharma, Tokyo, Japan.

Active ingredient: Amantadine (50 mg in 1 tablet).

Medical effects: Amantadine is an approved in Japan and USA medicine with several different clinical effects.

• it is effective in treating patients with Parkinson’s disease,
• it improves nervous system disorders,
• it treats uncomplicated respiratory tract illness caused by viruses,
• it’s used for treatment of drug-induced extrapyramidal reactions.

Contraindications and precautions: do not use in children, pregnant women and breastfeeding mothers. If an allergic reaction occurs, discontinue use. When used with other drugs, be sure to consult with your doctor.

Dosage and Administration of Symmetrel (Amantadine) 50 mg from Japan

For improving nervous system disorders: 2-3 tablets (100-150 mg) a day.

For Parkinson’s disease: start from 2 tablets (100 mg) a day. After 1 week increase the amount to 2 tablets 2 times a day (200 mg in a daily dose). The amount can be adjusted by a consulting doctor. But it should never exceed 300 mg a day.

Is Japanese Symmetrel (Amantadine) 50 mg effective medicine?

Symmetrel (Amantadine) 50 mg from Japan shows multiple antiviral activities like preventing the release of infectious viral nucleic acid into the host cell, preventing virus assembly during virus replication, inhibiting the replication of certain form of viruses. At the beginning of 2010s some researches start doubting in amantadine’s effectiveness in treating influenza virus. But resent studies proved that problem is not in Symmetrel’s antiviral properties but in defining which viruses exactly should be treated with amantadine (A. Hurt, N. Komadina et al. “Detection of adamantane-sensitive influenza A(H3N2) viruses in Australia, 2017: a cause for hope?” Euro Surveill. 2017 Nov;22(47); T. Niu, X. Zhao et al. “Evolution and Biological Evaluation of Matrinic Derivatives with Amantadine Fragments As New Anti-Influenza Virus Agents”. Molecules. 2019 Mar 6;24(5); W. Li, Y. L. Balachandran et al. “Amantadine Surface-Modified Silver Nanorods Improves Immunotherapy of HIV Vaccine Against HIV-Infected Cells”. ACS Applied Materials & Interfaces. 2018 Aug 29;10(34)).

Furthermore, a lot of studies prove Symmetrel’s effectiveness in treating Parkinson’s disease and nervous system disorders. (S. Naderi, H. Faghih et al. “Amantadine as adjuvant therapy in the treatment of moderate to severe obsessive-compulsive disorder: A double-blind randomized trial with placebo control”. Psychiatry and Clinical Neurosciences. 2019 Apr;73(4):169-174; M. Sreedharan, K. Devadathan et al. “Amantadine for the Treatment of Refractory Absence Seizures in Children”. Journal of Pediatric Neurosciences. 2018 Apr-Jun;13(2):131-136). That’s why Symmetrel (Amantadine) 50 mg stays very popular antiviral and antiparkinsonian medicine in Japan.