Ursodiol (ursodeoxycholic acid) 100 mg (gallstones, liver cirrhosis)

General information on Ursodiol (ursodeoxycholic acid) for treatment of gallstones and liver from Japan

Package details: 100 tablets

Manufacturer: Sawai Pharmaceutical, Japan. Established in Osaka in 1929.

Active ingredient: ursodeoxycholic acid (100 mg in 1 tablet)

Medical effect: ursodeoxycholic acid has multiple scientifically proven effects on human body. These include following:

• increasing bile secretion and improving bile flow,
• improving of liver function in chronic liver disease,
• dissolving cholesterol gallstones,
• improving dyspepsia after small intestine resection,
• treating primary biliary cirrhosis and chronic liver disease due to hepatitis C virus.

Contraindications and precautions: Do not use in children, pregnant women and breastfeeding mothers. Cannot be used for patients with complete biliary obstruction and fulminant hepatitis. If an allergic reaction occurs, discontinue use. When used with other drugs, be sure to consult with your doctor. Store away from direct sunlight, heat and moisture.

Dosage and administration of Ursodiol (ursodeoxycholic acid) from Japan.

For treatment of disease of biliary system or liver disease and improvement of liver function and dyspepsia: 1/2 tablet (50 mg of the active ingredient) at a time, 3 times a day.

For dissolution of cholesterol gallstones: 2 tablets (200 mg of the active ingredient) at a time, 3 times a day.

For improvement of liver function in primary biliary cirrhosis and chronic liver disease due to hepatitis C virus: 2 tablets (200 mg of the active ingredient) at a time, 3 times a day. The dosage may be adjusted according to age and symptoms by the consulting doctor. But the maximum daily dose of 900 mg should not be exceeded.

Is Ursodiol (ursodeoxycholic acid) from Japan effective?

Ursodiol (ursodeoxycholic acid) is a well-studied medicine with multiple scientifically proven effects. It improves liver function indices in both cholestatic and inflammatory chronic liver diseases (M. Podda, C. Ghezzi et al. “Effect of different doses of ursodeoxycholic acid in chronic liver disease”. Digestive Diseases and Sciences, 1989 Dec;34(12 Suppl):59S-65S). Ursodiol increases bile secretion and thereby improves the bile flow. Also, it features the ability to lower the level of cholesterol and to dissolve cholesterol gallstones (L. E. Simental-Mendía, M. Simental-Mendía et al. “Impact of ursodeoxycholic acid on circulating lipid concentrations: a systematic review and meta-analysis of randomized placebo-controlled trials”. Lipids in health and disease. 2019 Apr 6;18(1):88). Furthermore, ursodeoxycholic acid helps to treat disease of biliary system, to improve dyspepsia after small intestine resection and an inflammatory disease of small intestine. Moreover, ursodiol is effective against primary biliary cirrhosis and chronic liver disease due to hepatitis C virus.