Progeston Depot (Proluton, Makena) injections 125 mg for gynecological disorders

General information on Japanese Progeston Depot injections 125 mg from Japan for gynecological disorders

Package details: 10 ampoules

Manufacturer: Fuji Pharma Co., Ltd., Japan

Active ingredient: hydroxyprogesterone caproate (chemical formula C27H40O4)

Medical effect: Progeston Depot injections are effective for treatment of the following diseases and conditions:

• amenorrhea,
• functional uterine bleeding,
• infertility caused by luteal dysfunction,
• imminent premature birth,
• habitual premature birth,
• recurrent miscarriage.  

Contraindications and precautions: do not use in patients with heart, liver or kidney diseases. Do not use in patients with history of genital herpes. Do not use in pregnant women except the cases when used for the prevention of premature birth.

Dosage and administration of Japanese Progeston Depot injections 125 mg for gynecological disorders In most of cases please take as intramuscular injection, 65-125 mg of active ingredient (0.5 or 1 ampoule) 1 time a week. The consulting doctor may adjust the dosage according to symptoms.

How effective are Progeston Depot injections 125 mg from Japan for gynecological disorders?

Progeston Depot is a progestin medication used to prevent premature birth. Japanese gynecologists recommend to start using it from 16-20 week of the pregnancy up to the 36 weeks. It also decreases neonatal morbidity including lower rates of necrotizing enterocolitis, intraventricular hemorrhage and need for supplemental oxygen (P. J. Meis, M. Klebanoff et al. Prevention of recurrent preterm delivery by 17 alpha-hydroxyprogesterone caproate. The New England Journal of Medicine. June 2003, 348 (24): 2379–85).

Who should use Progeston Depot injections 125 mg from Japan?

Progeston Depot injections are used not only for preventing premature birth, but also for treatment of various gynecological disorders. Those include dysmenorrhea, premenstrual syndrome, fibrocystic breast disease, adenosis, and breast pain. Also, this medication can be used as a menopausal hormone replacement therapy in women. Moreover, Pregeston Depot injections are used as a part of therapy for endometrial cancer. Studies prove that hydroxyprogesterone caproate significantly extends life in women with the disease.